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LASSO provides strong variable selection capability, is suitable for handling high-dimensional data, and effectively reduces the risk of overfitting, though its results can be sensitive to the regularization parameter and performance may decrease in the presence of multicollinearity ( GPX3 encodes glutathione peroxidase 3, an important antioxidant enzyme primarily responsible for reducing oxidative damage by catalyzing the conversion of hydrogen peroxide into water ( This study further elucidated the potential mechanisms of GPX3 and MYC in RA through GSVA and GSEA analyses

Directions Ans: As a dietary supplement, take 2 capsules daily, or as directed by a healthcare practitioner

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The Sanger sequencing analysis was conducted in the Centre for PanorOmic Sciences, LKS Faculty of Medicine, the University of Hong Kong